Rheumatoid Arthritis
Conditions
Keywords
Early, severe
Brief summary
The purpose of this research is to observe the effects of RA over a long period in order to learn which of the early characteristics of patients' early RA predict future joint damage and disability. We also investigate whether certain treatments can prevent or slow the development of joint damage and disability. Additionally, the costs and effects of RA on the patient are studied in order to improve the methods used to measure these effects. Clinical, demographic, radiographic, and laboratory measures are taken by the rheumatologist in the office. In addition, patient questionnaires are mailed & completed by the patient and returned to the coordinating center at UCLA. All information obtained by these means will be studied in their effects on early, severe RA.
Detailed description
See Publications
Interventions
None listed
Sponsors
University of California, Los Angeles
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \>=6 swollen joints & \>=9 tender joints * symmetrical rheumatoid arthritis (RA) * \<= 2 years worth of symptoms * rheumatoid factor seropositivity
Exclusion criteria
* \<18 years old * Inability to see rheumatologist, complete questionnaires (lack of compliance) * \>2 years worth of symptoms
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Development of joint erosions in the early stages of RA | Baseline, Annual Follow-up | Measure joint erosions over time |
Countries
United States
Outcome results
None listed