Catechin Gargling for Influenza Infection

A Randomized Clinical Study of Catechin Gargling Effects on the Prevention of Influenza Infection

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00239213

Enrollment

400

Registered

2005-10-14

Start date

2005-11-30

Completion date

2006-04-30

Last updated

2006-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Influenza Infection

Keywords

catechins, gargling, healthy volunteers

Brief summary

The purpose of this study is to clarify the preventive effects of catechin gargling on the influenza infection.

Detailed description

In-vitro experimental studies have revealed that tea catechin extracts induce preventive effects on influenza infection. However, few studies have been conducted on the effects of tea gargling on influenza infection, and the clinical evidence is unclear. Also there have been no studies reported on the gargling effects with tea catechin extracts on the prevention of influenza infection.

Interventions

DRUGcatechin extracts (health food)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

20 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy volunteers * aged 20 to 65 years old * obtained written informed concent before participation * inoculated with influenza vaccine before entering the study

Exclusion criteria

* other gargling except water during the study * possessing tea allergy

Design outcomes

Primary

Measure	Time frame
Incidence rates of influenza infection during the study	—

Secondary

Measure	Time frame
severity of symptoms including complications and hospitalization	—

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026