Diabetes Mellitus, Adult Onset
Conditions
Keywords
Cinnamon, Diabetes mellitus, Hyperlipidemia, Insulin Resistance
Brief summary
The purpose of this study is to determine the effects of cinnamon on serum glucose and lipid levels in people with non-insulin dependent type 2 diabetes mellitus.
Detailed description
Forty people with non-insulin dependent type 2 diabetes mellitus will be randomized to receive either cinnamon or placebo for three months. The dose of cinnamon will be one gram daily. Fasting serum glucose, triglyceride, total cholesterol, LDL, HDL, and insulin levels will be measured at baseline and at 1, 2, and 3 months. HbA1c levels will be measured at baseline and at 3 months. Patients will be monitored for compliance, adverse effects, and dietary changes.
Interventions
DRUGCinnamon or placebo 500 mg capsule twice daily
Cinnamon 500 mg capsule twice daily or placebo capsule twice daily
Sponsors
National Center for Research Resources (NCRR)
University of Oklahoma
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Type 2 diabetes mellitus * HbA1C \> 6.0% * Age 18 and above * Able to obtain consent
Exclusion criteria
* Currently taking insulin * Pregnancy * End-stage renal disease * Hemolytic anemia * Cinnamon intolerance * Inability or unwillingness to adhere to study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Primary outcomes include HbA1c, glucose, total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides levels. | 3 months |
Countries
United States
Outcome results
None listed