Myocardial Infarction
Conditions
Keywords
Oxygen Consumption, Exercise, Rehabilitation
Brief summary
The purpose of this study is to investigate the effect of the standard rehabilitation offered by three hospital rehabilitation units in Norway, one in Trondheim, one in Ålesund and one in Levanger, compared to an interval treadmill training program. The subjects participating in the study are patients with myocardial infarction. The maximal oxygen consumption of the subjects will be tested before and after the training period.
Detailed description
The purpose of this study is to investigate the effect of the standard rehabilitation offered by three hospital rehabilitation units in Norway, one in Trondheim, one in Ålesund and one in Levanger, compared to an interval treadmill training program. The subjects participating in the study are patients with myocardial infarction. The maximal oxygen consumption of the subjects will be tested before and after the training period. Primary outcome: Maximal oxygen consumption Secondary outcomes: Blood values (for endothelial function, blood lipids, etc), flow mediated dilatation, quality of life (SF 36 and MacNew), weight, BMI, heart rate fall 1 minute after stopping the maximal treadmill test.
Interventions
BEHAVIORALExercise training
Standard exercise training at the hospital, two times per week for twelve weeks
Sponsors
Norwegian University of Science and Technology
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Myocardial infarction 2-12 weeks ago
Exclusion criteria
* Heart failure * limitations to walking on a treadmill * failure to reach a maximal pre-test(\> NYHA class II) * uncontrolled hypertension * COPD * pregnancy * kidney failure (creatinin \> 140) * drug abuse * left ventricle EF \< 30%
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in maximal oxygen consumption | baseline, after intervention and at 6 months | At baseline, following intervention and at 6 months after the intervention. An additional follow-up test will be conducted in all patients who want to participate during 2009. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| flow mediated dilatation | baseline, after intervention and at 6 months | flow mediated dilatation (endothelial function) |
| echocardiography | baseline, after intervention and at 6 months | — |
| blood markers | baseline, after intervention and at 6 months | — |
| quality of life | baseline, after intervention and at 6 months | — |
Countries
Norway
Outcome results
None listed