Skip to content

Improving Safety By Computerizing Outpatient Prescribing

Improving Safety By Computerizing Outpatient Prescribing

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00235027
Enrollment
701
Registered
2005-10-10
Start date
2000-08-31
Completion date
2010-12-31
Last updated
2015-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impact of Electronic Prescribing on Medication Safety

Brief summary

Patient safety is at the forefront of critical issues in health care. Medications are the single most frequent cause of adverse events, and in the inpatient setting adverse drug events (ADEs) are common, expensive, injurious to patients, and often preventable. Relatively little, however, is known about the frequency of ADEs in the ambulatory setting, how to monitor for outpatient ADEs, or on the impact of prevention strategies such as computerization of prescribing supplemented by decision-support.

Detailed description

Specific Aim 1: Increase routine identification of outpatient adverse drug events (ADEs) through development of a computerized ADE detection monitor. Specific Aim 2: Use basic computerized outpatient prescribing to reduce preventable ADEs in a diverse array of outpatient settings. Specific Aim 3: Use advanced decision-support within computerized prescribing to reduce the frequency of preventable ADEs, medication errors, and potential ADEs.

Interventions

OTHERAdverse Drug Event Monitoring

The intervention in this study is the presentation of medication safety alerts in the electronic medical record to improve patient outcomes and safety.

Sponsors

Agency for Healthcare Research and Quality (AHRQ)
Lead SponsorFED

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Caregiver)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

At Brigham & Women's Hospital, clinics utilizing the electronic medical record will be included. At Regenstrief, any clinic that has access to their electronic medical record will be utilized. * For the impact of basic decision support, clinics were not randomized * For impact of advanced decision support, clinics were randomized to receive the intervention

Exclusion criteria

* Clinics not using electronic medical records

Design outcomes

Primary

MeasureTime frameDescription
Preventable Adverse drug events8/5/2004 - 1/5/2005Data were electronically collected each time a physician entered a prescription that triggered an alert related to medication safety.

Secondary

MeasureTime frame
Total adverse drug events, medication errors1/15/2001 - 5/15/2001

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026