Russian Study of the Efficacy and Safety of Tarka in Patients With Hypertension

A Multicenter, Open, Phase IV, 24-Hour Ambulatory Blood Pressure Monitoring Study of the Efficacy and Safety of Tarka in Patients With Arterial Hypertension

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00235001

Enrollment

120

Registered

2005-10-10

Start date

2004-06-30

Completion date

Unknown

Last updated

2008-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Keywords

Hypertension, Tarka

Brief summary

This study will investigate antihypertensive activity and safety profile of Tarka in Russian hypertension patients by ambulatory blood pressure measurement (ABPM)

Interventions

DRUGtrandolapril/verapamil

180/2 mg QD

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Hypertension

Exclusion criteria

* SBP \> 180 mm Hg, DBP \> 114 mm Hg * Subject has a hypersensitivity to trandolapril or verapamil

Design outcomes

Primary

Measure	Time frame
Change in blood pressure from baseline/blood pressure control	Baseline to 3 months of Tx

Secondary

Measure	Time frame
Absolute BP reduction from baseline, safety	Baseline to 3 months of Tx

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026