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Efficacy of Naltrexone Treatment as Augmentation to SSRI in OCD Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00234689
Enrollment
Unknown
Registered
2005-10-07
Start date
2002-01-31
Completion date
2004-12-31
Last updated
2008-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive Compulsive Disorder

Brief summary

Assessing the efficacy of Naltrexone as augmentation to SSRI in patients with OCD

Interventions

DRUGNaltrexone

Sponsors

Sheba Medical Center
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Masking
DOUBLE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosis of OCD * Treatment with SSRI for at least 10 weeks with no response

Exclusion criteria

* Suffering from any medical condition * treatment with opiates * chronic use of drugs * Hepatitis or other liver related diseases * Incapability to sign an informed consent

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026