Death, Dyspnea, Pain
Conditions
Keywords
Palliative Care, Terminal Care, Hospice Care, Patient Care Planning, Nursing Care Plans, Quality of Health Care, Inpatients, Professional education, Resuscitation orders, Pastoral Care
Brief summary
The BEACON trial (Best Practices for End-of-Life Care for Our Nations' Veterans) was a six-site implementation study to evaluate a multi-component, education-based intervention to improve the quality of end-of-life care provided in VA Medical Centers.
Detailed description
The BEACON trial (Best Practices for End-of-Life Care for Our Nations' Veterans) was a six-site, real-world implementation trial of a multi-component, education-based intervention to improve the quality of end-of-life care conducted in VA Medical Centers (VAMCs). The primary aim was to evaluate the effectiveness of a multi-component intervention for improving processes of care provided in the last days of life in VAMCs. The second aim was to conduct after-death interviews with next-of-kin and qualitative analysis of their perceptions of the care provided to the veteran and family. The multi-component intervention targeted VAMC inpatient providers, including physician, nursing, and ancillary staff. It consisted of preparatory site visits, a staff training program, a newly developed Comfort Care order set decision support tool built into the CPRS, and follow-up consultation. The intervention team travelled to each site to conduct two weeks of comprehensive in-service training. Staff were trained to identify actively-dying patients and implement a set of best practices of traditionally home-based hospice care for dying patients. The team provided assistance with policies, procedures, and skill training needed to implement comfort care interventions. Introduction of the intervention at each VAMC was staggered across time at six-month intervals using a multiple-baseline, stepped wedge design. Data on processes of end-of-life care (last 7 days) were abstracted from the CPRS medical records of all veterans who died before, during, and after the intervention (January 2005-February 2011). A priori, five processes of care were identified as primary endpoints to indicate quality of end-of-life care: 1) presence of an order for opioid pain medication at time of death; 2) a do-not-resuscitate (DNR) order in place at time of death; 3) location of death; 4) presence of enteral feeding tube or intravenous line at time of death; and 5) physical restraints in place at or near time of death. In addition, in-depth, face-to-face interviews were conducted with 78 bereaved next-of-kin.
Interventions
Comfort care education intervention, consisting of intensive, on-site staff training together with an electronic order set for palliative care and educational materials
Sponsors
Study design
Eligibility
Inclusion criteria
* Aim 1: Not applicable. Patients were deceased. * Aim 2: After-death interviews with next of kin: must be willing and able to participate in after-death interview at local VA Medical Center.
Exclusion criteria
* N/A
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Presence of Order for Opioid Pain Medication | Pre and Post Intervention | Presence of order for opioid pain medication at time of death based on abstraction of electronic medical record |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Do Not Resuscitate Order | Pre and Post Intervention | Presence of a Do Not Resuscitate order at time of death based on abstraction of electronic medical record |
| Number of Patients Who Died in ICU | Pre and Post Intervention | Location of death (ICU vs. other) based on abstraction of electronic medical record |
| Individuals With a Nasogastric Tube | Pre and Post Intervention | Presence of nasogastric tube based on abstraction of electronic medical record |
| Number of Individuals Who Died in Restraints | Pre and Post Intervention | Presence of restraints at or near time of death at time of death based on abstraction of electronic medical record |
| Individuals Administered of Opioid Medication | Pre and Post Intervention | Administration of opioid medication based on abstraction of medical record |
| Individuals With an Order for Antipsychotic Medication | Pre and Post Intervention | Order for antipsychotic medication based on abstraction of medical record |
| Individuals Administered Antipsychotic Medication | Pre and Post Intervention | Administration of antipsychotic medication based on abstraction of medical record |
| Individuals With an Intravenous Line | Pre and Post Intervention | Presence of intravenous line infusing at time of death based on abstraction of electronic medical record |
| Individuals Who Received Benzodiazepine Medication | Pre and Post Intervention | Administration of benzodiazepine medication based on abstraction of medical record |
| Individuals Who Received Scopolamine | Pre and Post Intervention | Administration of scopolamine (for death rattle) based on abstraction of medical record |
| Sublingual Administration | Pre and Post Intervention | Sublingual administration of medication based on abstraction of medical record |
| Individuals With Pastoral Care Visit | Pre and Post Intervention | Pastoral Care Visit based on abstraction of medical record |
| Individuals With an Advance Directive | Pre and Post Intervention | Presence of advance directive based on abstraction of medical record |
| Individuals With a Palliative Care Consultation | Pre and Post Intervention | Palliative Care Consultation based on abstraction of medical record |
| Individuals With an Order for Benzodiazepine Medication | Pre and Post Intervention | Order for benzodiazepine medication based on abstraction of medical record |
Countries
United States
Participant flow
Recruitment details
The BEACON trial implemented an intervention to improve quality of care at end of life. Six Veterans Administration Hospitals received the intervention in a pre-post design. Outcomes were abstracted for 6066 individuals who died either pre or post intervention. 78 next-of-kin were enrolled under protocol to conduct qualitative interviews.
Pre-assignment details
The BEACON trial implemented an intervention to improve quality of care at end of life. Six Veterans Administration Hospitals received the intervention in a pre-post design. Outcomes were abstracted for 6066 individuals who died either pre or post intervention. 78 next-of-kin were enrolled under protocol to conduct qualitative interviews.
Participants by arm
| Arm | Count |
|---|---|
| Arm 1 Comfort care education intervention, consisting of on-site staff training together with an electronic order set for palliative care and educational materials
Comfort care education intervention: Comfort care education intervention, consisting of on-site staff training together with an electronic order set for palliative care and educational materials | 6,066 |
| Total | 6,066 |
Baseline characteristics
| Characteristic | Arm 1 |
|---|---|
| Age, Continuous | 71.2 years STANDARD_DEVIATION 12 |
| Gender Female | 109 participants |
| Gender Male | 5812 participants |
| Race/Ethnicity, Customized Asian | 1 participants |
| Race/Ethnicity, Customized Black | 1876 participants |
| Race/Ethnicity, Customized Hispanic black | 2 participants |
| Race/Ethnicity, Customized Hispanic white | 8 participants |
| Race/Ethnicity, Customized Native American | 4 participants |
| Race/Ethnicity, Customized Native Hawaiian/Pacific Islander | 4 participants |
| Race/Ethnicity, Customized White | 3528 participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 0 / 0 |
| serious Total, serious adverse events | 0 / 0 |
Outcome results
Presence of Order for Opioid Pain Medication
Presence of order for opioid pain medication at time of death based on abstraction of electronic medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Presence of Order for Opioid Pain Medication | 2004 participants |
| Post-Intervention | Presence of Order for Opioid Pain Medication | 2056 participants |
Do Not Resuscitate Order
Presence of a Do Not Resuscitate order at time of death based on abstraction of electronic medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Do Not Resuscitate Order | 2282 participants |
| Post-Intervention | Do Not Resuscitate Order | 2127 participants |
Individuals Administered Antipsychotic Medication
Administration of antipsychotic medication based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals Administered Antipsychotic Medication | 224 participants |
| Post-Intervention | Individuals Administered Antipsychotic Medication | 280 participants |
Individuals Administered of Opioid Medication
Administration of opioid medication based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals Administered of Opioid Medication | 1569 participants |
| Post-Intervention | Individuals Administered of Opioid Medication | 1662 participants |
Individuals Who Received Benzodiazepine Medication
Administration of benzodiazepine medication based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals Who Received Benzodiazepine Medication | 710 participants |
| Post-Intervention | Individuals Who Received Benzodiazepine Medication | 675 participants |
Individuals Who Received Scopolamine
Administration of scopolamine (for death rattle) based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals Who Received Scopolamine | 113 participants |
| Post-Intervention | Individuals Who Received Scopolamine | 633 participants |
Individuals With an Advance Directive
Presence of advance directive based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals With an Advance Directive | 1194 participants |
| Post-Intervention | Individuals With an Advance Directive | 1306 participants |
Individuals With a Nasogastric Tube
Presence of nasogastric tube based on abstraction of electronic medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals With a Nasogastric Tube | 1293 participants |
| Post-Intervention | Individuals With a Nasogastric Tube | 922 participants |
Individuals With an Intravenous Line
Presence of intravenous line infusing at time of death based on abstraction of electronic medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals With an Intravenous Line | 2004 participants |
| Post-Intervention | Individuals With an Intravenous Line | 2056 participants |
Individuals With an Order for Antipsychotic Medication
Order for antipsychotic medication based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals With an Order for Antipsychotic Medication | 336 participants |
| Post-Intervention | Individuals With an Order for Antipsychotic Medication | 661 participants |
Individuals With an Order for Benzodiazepine Medication
Order for benzodiazepine medication based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals With an Order for Benzodiazepine Medication | 1102 participants |
| Post-Intervention | Individuals With an Order for Benzodiazepine Medication | 1185 participants |
Individuals With a Palliative Care Consultation
Palliative Care Consultation based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals With a Palliative Care Consultation | 184 participants |
| Post-Intervention | Individuals With a Palliative Care Consultation | 885 participants |
Individuals With Pastoral Care Visit
Pastoral Care Visit based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Individuals With Pastoral Care Visit | 1630 participants |
| Post-Intervention | Individuals With Pastoral Care Visit | 1765 participants |
Number of Individuals Who Died in Restraints
Presence of restraints at or near time of death at time of death based on abstraction of electronic medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Number of Individuals Who Died in Restraints | 531 participants |
| Post-Intervention | Number of Individuals Who Died in Restraints | 362 participants |
Number of Patients Who Died in ICU
Location of death (ICU vs. other) based on abstraction of electronic medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Number of Patients Who Died in ICU | 1312 participants |
| Post-Intervention | Number of Patients Who Died in ICU | 1046 participants |
Sublingual Administration
Sublingual administration of medication based on abstraction of medical record
Time frame: Pre and Post Intervention
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Pre-Intervention | Sublingual Administration | 122 participants |
| Post-Intervention | Sublingual Administration | 322 participants |