Asthma
Conditions
Keywords
Children of asthmatic mothers
Brief summary
This prospective study will evaluate the feasibility of the defined decision tree for the treatment of asthmatic young children. Children who develop episode (=3 consecutive days) of any troublesome lower respiratory symptoms are treated according to a strictly pre-defined multi-steps treatment algorithm until the age of 6 years.
Interventions
PROCEDUREPulmicort (budesonide) pMDI
Sponsors
AstraZeneca
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 6 Years
Healthy volunteers
No
Inclusion criteria
* Children form the COPSAC/PAC study with episodes of troublesome respiratory symptoms. Episodes are defined as 3 consecutive days of any troublesome lower respiratory symptoms.
Exclusion criteria
* Differential diagnoses including at least a chest x-ray and sweat test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of the treatment algorithm: Frequency of protocol deviations, asthma exacerbations, different treatment steps. | — |
| Efficacy - development of lung function. | — |
Secondary
| Measure | Time frame |
|---|---|
| Acceptability of the treatment algorithm by the parents. | — |
| Growth rate and BMD. | — |
| Exhaled nitrogen Oxide, bronchohyperresponsiveness. | — |
Countries
Denmark
Outcome results
None listed