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Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count

Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00231504
Enrollment
82
Registered
2005-10-04
Start date
2005-10-31
Completion date
2009-05-31
Last updated
2010-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antral Follicle Deficit, Fertility

Keywords

Polymorphism P1, Polymorphism P2, FSH Receptor, Antral follicle count, FSH receptor polymorphism

Brief summary

The deficit in the total number of antral follicles is associated with a reduction of the ovarian fertility potential in young women. The principal objective of this study is to evaluate the relationship between FSH receptor polymorphism and antral follicle count. The investigators have designed a study of FSH receptor polymorphisms P1 and P2 as an association with a low antral follicle count in the ovary.

Detailed description

The present study will compare the prevalence of FSH receptor polymorphisms P1 and P2 in women having reduced follicle count (1 to 9 antral follicles) or normal follicle count (13 to 20 antral follicles) determined by ultrasound scans.

Interventions

PROCEDUREBlood samples

Blood samples

Sponsors

Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* 18 to 35 years old * 1 to 9 or 13 to 20 antral follicles * Caucasian, occidental Europe * Presence of both ovaries * Informed consent

Exclusion criteria

* Ovarian anomalies * Menopause * Pregnancy * Other diseases

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026