Antral Follicle Deficit, Fertility
Conditions
Keywords
Polymorphism P1, Polymorphism P2, FSH Receptor, Antral follicle count, FSH receptor polymorphism
Brief summary
The deficit in the total number of antral follicles is associated with a reduction of the ovarian fertility potential in young women. The principal objective of this study is to evaluate the relationship between FSH receptor polymorphism and antral follicle count. The investigators have designed a study of FSH receptor polymorphisms P1 and P2 as an association with a low antral follicle count in the ovary.
Detailed description
The present study will compare the prevalence of FSH receptor polymorphisms P1 and P2 in women having reduced follicle count (1 to 9 antral follicles) or normal follicle count (13 to 20 antral follicles) determined by ultrasound scans.
Interventions
Blood samples
Sponsors
Study design
Eligibility
Inclusion criteria
* 18 to 35 years old * 1 to 9 or 13 to 20 antral follicles * Caucasian, occidental Europe * Presence of both ovaries * Informed consent
Exclusion criteria
* Ovarian anomalies * Menopause * Pregnancy * Other diseases
Countries
France