Croup
Conditions
Keywords
croup, humidity therapy, pediatrics
Brief summary
Croup affects 5% of children under 6 years of age, resulting in visits to hospital Emergency Departments, and in 1% of children, hospitalization. Traditionally, the first therapy offered is humidification which can liquify airway secretions and decrease airway swelling. This study will compare the effectivenesss of 40% and 100% humidity through a specially designed machine called a nebulizer, with the usual humidity set-up (blown into the patient's face from a hose).
Interventions
DEVICEnebulized humidity
Sponsors
The Physicians' Services Incorporated Foundation
The Hospital for Sick Children
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Age
3 Months to 10 Years
Healthy volunteers
No
Inclusion criteria
* children aged 3 months - 10 years * croup score greater than or equal to 2 after a 30 minute waiting period
Exclusion criteria
* Symptoms of croup requiring immediate intervention with nebulized epinephrine or intubation * symptoms or signs of alternative causes of stridor * inability of caregivers to understand or speak English and/or sign for informed consent * history of chronic pulmonary disease except for asthma, or co-existent systemic disease * previous history of intubation * duration of present illness \>1 week * systemic or inhaled glucocorticoids in previous 48 hours * epinephrine in previous 4 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in the croup score from baseline to 30 and 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| steroid or epinephrine treatment at 60 minutes | — |
| discharge rate at 60 minutes | — |
| change in pulse, respiratory rate, and oxygen saturation at 60 minutes | — |
Countries
Canada
Outcome results
None listed