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Assessing CPR Quality During In-Hospital Cardiac Arrest

Assessment of Cardiopulmonary Resuscitation Quality During In-Hospital Cardiac Arrest

Status
Terminated
Phases
Phase 2Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00228293
Enrollment
200
Registered
2005-09-28
Start date
2002-12-31
Completion date
2005-09-30
Last updated
2013-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest

Keywords

cardiac arrest, CPR

Brief summary

Using an investigational monitor/defibrillator that passively records CPR quality parameters, including chest compression rate and depth and ventilation rate and volume, we are prospectively recording CPR quality during sequential in-hospital cardiac arrests at the University of Chicago Hospitals. Using an audio feedback system linked to this device, we are studying whether such audio feedback improves CPR quality when provided to rescuers trained in the use of the device.

Detailed description

Patients who suffer cardiac arrest during their hospitalization at the University of Chicago hospitals are given CPR and other resuscitation measures by trained physician and nurse teams. This care is given with the use of defibrillators to monitor cardiac rhythm as well as provide defibrillation as needed. We have worked closely with engineers at Laerdal Medical Corporation to develop a defibrillator that passively monitors the quality of CPR via additional external sensors (see details in the following reference: Abella BS, Alvarado JP, Myklebust H, Edelson DP, Barry A, O'Hearn N, Vanden Hoek TL, Becker LB. Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. JAMA. 2005;293:305-10). Patients who suffer in-hospital arrest are enrolled (provided they are over 16 years of age, are not pregnant, and are not in the operating room or emergency room setting) with mechanisms to satisfy IRB waiver of consent provisions. These patients receive the same care as before the study, but CPR parameters are recorded by the device. In addition, the device provides audio/visual coaching in CPR, based on the actual performance of CPR as measured. We hypothesize that this coaching will improve CPR quality and hopefully improve survival from cardiac arrest. The first phase of investigation is now complete, where patients were enrolled and studied without feedback (baseline group). Now we are enrolling patients into a second group with feedback provided. Enrollment is nearly complete for this second group. We will then evaluate the baseline and feedback groups to ascertain whether CPR improved over the two cohorts.

Interventions

DEVICEinvestigational monitor/defibrillator with CPR feedback

Sponsors

Laerdal Medical
CollaboratorINDUSTRY
University of Chicago
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* adult patient with cardiac arrest hospitalized at University of Chicago Hospitals

Exclusion criteria

* pregnant * arrest in ER or OR * pediatric patient * patient DNR, no CPR given * no CPR given for other reasons (e.g. shock only)

Design outcomes

Primary

MeasureTime frame
CPR pause times
ventilation rate
ventilation depth
parameters of CPR quality:
chest compression rate
chest compression depth

Secondary

MeasureTime frame
survival to hospital discharge
return of spontaneous circulation (ROSC)

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 8, 2026