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Promoting Long-term Behavior Change to Reduce CVD Risk

Promoting Long-term Dietary Change to Reduce CVD Risk

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00227006
Enrollment
163
Registered
2005-09-27
Start date
1999-01-31
Completion date
2004-04-30
Last updated
2015-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Brief summary

Once intervention class or staff contact is removed, obese adults participating in behavioral weight-loss programs often give up healthy eating habits and regain weight. We examined whether taste-based goal setting, which minimizes perceived deprivation by promoting taste and moderation, would sustain long-term reductions in saturated fat and body mass index (BMI).

Detailed description

Once intervention class or staff contact is removed, obese adults participating in behavioral weight-loss programs often give up healthy eating habits and regain weight. We examined whether taste-based goal setting, which minimizes perceived deprivation by promoting taste and moderation, would sustain long-term reductions in saturated fat and body mass index (BMI). Participants were randomized to Taste-Based Choices (taste-based goal setting + a standard 6-month behavioral weight-loss intervention), Smart Consumers (a standard 6-month intervention alone) or Community Access (access to commercial/community-based behavioral weight-loss programs) and followed over 18 months. To test our hypotheses, we examined a set of orthogonal contrasts (TBC and SC vs. CA; TBC vs. SC) on reductions in saturated fat (Block FFQ) and clinic-measured BMI.

Interventions

BEHAVIORALBehavioral lifestyle/weight-loss intervention

Sponsors

National Heart, Lung, and Blood Institute (NHLBI)
CollaboratorNIH
Unrestricted research gift from Nutrilite Health Institute
CollaboratorUNKNOWN
Stanford University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
25 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

- Body mass index between 27-37 * Physically inactive * Able to participate in physical activity * Percentage of daily calories from total fat 30% or more * Free of diagnosed heart disease * Stable on medications for 3 months or more

Exclusion criteria

- Diabetic * Dysphoric (Beck Depression Inventory score greater than 18) * Binge eating or bulimic (Eating Disorder Diagnostic Scale)

Design outcomes

Primary

MeasureTime frame
Percentage of saturated fat in diet18 months

Secondary

MeasureTime frame
Body weight18 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026