Skip to content

Stress, Diurnal Cortisol, and Breast Cancer Survival

Stress, Diurnal Cortisol, and Breast Cancer Survival

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00226967
Enrollment
115
Registered
2005-09-27
Start date
2002-09-08
Completion date
2005-12-31
Last updated
2020-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Brief summary

The purpose of this study is to learn about the effects of stress on hormones, the relationship between these hormones and cancer progression.

Detailed description

The purpose of this study is to investigate stress and tonic activation of diurnal cortisol in aging metastatic breast cancer patients; feedback inhibition & activation of cortisol; and stress-induced phasic activation of cortisol.

Interventions

Calculated per patient

Sponsors

National Institute on Aging (NIA)
CollaboratorNIH
Stanford University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
35 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Diagnosis of recurrent or metastatic breast cancer. 2. Karnofsky of 70% or greater. 3. Proficient enough in English to be able to take questionnaires and participate in the required tasks. 4. Living within the Greater Bay Area. 5. Age 35 or older .

Exclusion criteria

1. Positive supraclavicular lymph nodes as the only metastatic lesion at the time of initial diagnosis. 2. Active cancers within the past 10 years other than breast cancer, basal cell or squamous cell carcinomas of the skin, or in situ cancer of the cervix. 3. Any other serious medical condition that will effect short term survival 4. History of major psychiatric illness for which patient was hospitalized or medicated, with the exception of depression or anxiety 5. A diagnosis of diabetes.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026