Seasonal Allergic Rhinitis
Conditions
Keywords
driving, memory
Brief summary
On-the-road driving performance of untreated seasonal allergic rhinitis patients during the allergic season (exposed) is compared to driving performance outside the allergic season (in winter, not-exposed).
Detailed description
This study was set-up to examine whether untreated seasonal allergic rhinitis has an effect on driving ability. In addition to the driving tests, patients perform a memory test in the laboratory.
Interventions
OTHER1 week of treatment discontinuation
1 week of treatment discontinuation during allergic rhinitis season
Sponsors
UCB Pharma
Utrecht Institute for Pharmaceutical Sciences
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* outpatients with seasonal allergic rhinitis * a valid driver's licence * written informed consent * a T5SS score \>8 during the allergic season and \<3 in winter
Exclusion criteria
* use of medication or medical conditions that are known to affect driving ability * associated ENT disease or asthma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Driving test: Standard Deviation of Lateral Position (SDLP, cm); i.e. the weaving of the car [after 1 week of treatment discontinuation] | allergic season and winter |
Secondary
| Measure | Time frame |
|---|---|
| Other driving test parameters: standard deviation of speed, mean speed, meal lateral position [after 1 week of treatment discontinuation] | allergic season and winter |
| Memory test: immediate and delayed recall, delayed recognition [after 1 week of treatment discontinuation] | allergic season and winter |
Countries
Netherlands
Outcome results
None listed