ADHD
Conditions
Keywords
adult
Brief summary
The primary purpose of this study is to determine the effects of methylphenidate versus placebo on driving ability of adult ADHD patients.
Detailed description
This study was set-up to examine the controversial issue whether or not it is safe to drive a car or not when treated with methylphenidate. On-the-road driving tests during normal traffic are conducted to determine the effects of methylphenidate versus placebo on driving ability of adult ADHD patients.In addition, two laboratory tests are conducted to examine memory functioning and inhibitory control.
Interventions
DRUGmethylphenidate
Sponsors
Utrecht Institute for Pharmaceutical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
DOUBLE
Eligibility
Sex/Gender
ALL
Age
21 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* adult ADHD patient over 21 years old * valid driver's license for at least 3 years * treated with methylphenidate * written informed consent
Exclusion criteria
* use of illicit drugs * use of drugs or having medical conditions known to affect driving ability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Driving test:Standard Deviation of Lateral Position (SDLP, cm);i.e. the weaving of the car [single dose effects] | — |
Secondary
| Measure | Time frame |
|---|---|
| Other Driving test parameters: Standard Deviation of Speed, mean speed, mean lateral position. | — |
| Memory test: immediate & delayed word recall, delayed recognition.[single dose effects] | — |
| Continuous Performance test: RT, %errors [single dose effects] | — |
Countries
Netherlands
Outcome results
None listed