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Schizophrenia, Antipsychotic Treatment and the Risk for Diabetes Mellitus

Schizophrenia, Antipsychotic Treatment and the Risk for Diabetes Mellitus

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00222807
Enrollment
200
Registered
2005-09-22
Start date
2003-08-31
Completion date
2016-03-31
Last updated
2017-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delusional Disorder, Schizoaffective Disorder, Schizophrenia

Keywords

schizophrenia, psychosis, type 2 diabetes mellitus

Brief summary

This preliminary study aims to investigate the mechanism of higher rates of type 2 diabetes mellitus in patients with schizophrenia. As part of the study, we collect neuroendocrine-immune data on patients with first episode, treatment naive psychosis, patients with newly diagnosed schizophrenia and normal healthy controls. Regardless the treatment status, we collect the same neuroendocrine-immune data on the participants after 2 months.

Detailed description

This preliminary study aims to investigate the mechanism of higher rates of type 2 diabetes mellitus in patients with schizophrenia. As part of the study, we collect neuroendocrine-immune data on patients with first episode, treatment naive psychosis, patients with newly diagnosed schizophrenia and normal healthy controls. Regardless the treatment status, we collect the same neuroendocrine-immune on the participants (patients and controls) after 2 months. Thus, our study does not control treatment. Patients take treatment in consultation with their physician. Some of them even decide not to take any medications. At the 2nd visit, we do ask them about the the medications they are taking if any.

Interventions

None listed

Sponsors

American Association for Geriatric Psychiatry
CollaboratorOTHER
Janssen Pharmaceuticals
CollaboratorINDUSTRY
University of Pittsburgh
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
14 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Psychotic disorder as per DSM-IV criteria of the American Psychiatric Association

Exclusion criteria

* Diabetes, type 1 or 2 * Prominent substance abuse (i.e. psychotic symptoms attributable entirely to substance use) * Age above 50 or age below 14

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026