HIV Infections
Conditions
Keywords
HIV Infection, Acute HIV Infection, Primary HIV Infection, Acute Seroconversion Syndrome
Brief summary
To study the collection of blood from individuals known to be at high risk for HIV-infection or who have been recently infected with HIV. The data collected are used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment Guidelines.
Detailed description
This phlebotomy protocol permits the collection of blood from individuals known to be at high risk for HIV-infection or who have been recently infected with HIV. Participants will have from 10 to 60 ml (approximately 1 to 4 tablespoons) of blood drawn for one or all of the following tests: * T cell subset enumeration * Serologic reactivity with HIV antigens * Viral load assays by bDNA, PCR, or RT-PCR * Routine Laboratory assessments (chemistries, liver function tests, hepatitis serology, RPR) * HIV-1 Resistance Testing These data are used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment Guidelines
Interventions
OTHERblood draw
* T cell subset enumeration * Serologic reactivity with HIV antigens * Viral load assays by bDNA, PCR, or RT-PCR * Routine Laboratory assessments (chemistries, liver function tests, hepatitis serology, RPR) * HIV-1 Resistance Testing
Sponsors
Rockefeller University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
recently infected with HIV-1 HIV-1 negative, and at high risk for infection
Exclusion criteria
none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Participants are tested for HIV-1 RNA levels, the presence of antibodies to HIV antigens, and T cell subsets | first visit |
Secondary
| Measure | Time frame |
|---|---|
| Data will be used for diagnostic, prognostic and management decisions as outlined by current HIV-1 Treatment | first visit |
Countries
United States
Outcome results
None listed