Nasogastric Tube in Premature Babies - Pain and Treatment

Nasogastric Tube in Premature Babies - Pain and Treatment. A Randomised, Partly Blinded, Placebo-controlled Factorial Clinical Trial of Sucrose and Pacifier

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00218946

Enrollment

Registered

2005-09-22

Start date

2005-01-31

Completion date

2007-08-31

Last updated

2015-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant, Premature

Keywords

pain, infant, premature, intubation, gastrointestinal, Neonatal nursing

Brief summary

Does sucrose or pacifier influence pain in premature babies when a nasogastric tube is inserted?

Detailed description

A total of 24 premature babies are randomised to receive either placebo (sterile water), 30 % sucrose, or pacifier in a complete factorial, cross-over design. Pain is rated on the PIPP scale by observers blinded to the procedure other than use of pacifier.

Interventions

DRUGSucrose

30 % sucrose

DEVICEPacifier

OTHERsterile water

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Masking

SINGLE (Caregiver)

Eligibility

Sex/Gender

ALL

Age

3 Days to 8 Weeks

Healthy volunteers

Yes

Inclusion criteria

* 28 - 32 weeks gestational weeks * not on mechanical ventilation

Exclusion criteria

* high risk group regarding cerebral prognosis

Design outcomes

Primary

Measure	Time frame
Pain measured on PIPP (Premature Infant Pain Profile) scale	4 week to complete

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026