Pediatric Heart Transplant
Conditions
Keywords
Epstein-Barr virus, pediatric health, cardiac, heart transplant, lymphoproliferative disease, post-transplant, pediatric transplant
Brief summary
The purpose of this study is to determine the significance of an elevated quantitative EBV PCR and to determine the relationship between a EBV PCR value and the risk of developing PTLD.
Detailed description
The relationship between Epstein-Barr virus and lymphoproliferative disease has been established, particularly in the immuno-suppressed patient. Over the past several years a quantitative EBV PCR lab test has been established. Unfortunately, the significance of an elevated test remains unclear. The relationship of a particular EBV PCR value and the risk of developing PTLD is unknown. The primary aims will be to determine the significance of an elevated quantitative EBV PCR and to determine the relationship between a EBV PCR value and the risk of developing PTLD. The study will be conducted through a retrospective chart review of approximately 160 patients and we will look at postoperative data including Quantitative EBV PCR results, the presence / absence of PTLD and the treatment of PTLD and results of EBV PCR with treatment.
Interventions
None listed
Sponsors
Children's Healthcare of Atlanta
Study design
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patients undergone pediatric heart transplant * followed by pediatric heart transplant program
Exclusion criteria
\-
Countries
United States
Outcome results
None listed