Detection of Plasma DNA in Non Small Cell and Small Cell Lung Cancer Patients

Detection of Plasma DNA by Allelotyping in Non Small Cell and Small Cell Lung Cancer Patients. Evolution During Treatment and Follow-up.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00213798

Enrollment

200

Registered

2005-09-21

Start date

2003-12-31

Completion date

2011-08-31

Last updated

2025-12-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-Small Cell Lung Carcinoma, Small Cell Lung Cancer

Keywords

Lung cancer, plasma DNA, allelotyping, follow-up, Prospective Study, Non-Small Cell Lung Cancer, Small Cell Lung Cancer

Brief summary

The majority of lung cancer patients have a tumor-derived genetic alteration in circulating plasma DNA that could be exploited as a diagnostic tool. The aim of this study is to evaluate if plasma DNA can be used as a valuable non invasive test to monitor disease progression without assessing the tumor.

Interventions

PROCEDUREBiopsy samples

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Presence of lung tumor to use fiberoscopy or surgical intervention for diagnosis. * No lung instability. * Individuals give all informed consent

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026