Controlled Study of ONO-1101 in Patients With Postoperative Tachyarrhythmias in Japan

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00212680

Enrollment

100

Registered

2005-09-21

Start date

1996-12-31

Completion date

Unknown

Last updated

2012-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Supraventricular Tachyarrythmia

Keywords

ONO-1101,Landiolol Hydrochloride, Postoperative, Supraventricular Tachyarrhythmia

Brief summary

The purpose of this study was to evaluate the dose-dependent effects of ONO-1101 on efficacy and safety in patients with postoperative supraventricular tachyarrhythmias.

Interventions

DRUGONO-1101

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to 79 Years

Healthy volunteers

Inclusion criteria

1. 20-80 years old 2. Postoperative supraventricular tachyarrhythmias (sinus tachycardia, those with a heart rate of 120 beats/min or higher, and supraventricular arrhythmia, those with a heart rate of 100 beats/min or higher) 3. Within 7 days postoperatively 4. Other inclusion criteria as specified in the protocol

Exclusion criteria

1. Acute myocardial infarction (within 1 month after onset) 2. Severe heart failure (New York Heart Association functional class III or higher) 3. Atrioventricular block (grade II or higher),or sick sinus syndrome 4. Other

Design outcomes

Primary

Measure	Time frame
Percentage of patients achieving 20% reduction in heart rate at each dose	—

Secondary

Measure	Time frame
Heart Rate, Blood pressure and 12-lead ECG	—

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026