Tuberculosis
Conditions
Brief summary
To create a Tuberculosis Research Blood Bank for future molecular genetics and serological studies
Interventions
PROCEDUREDevelop a bank of blood samples from patients infected with TB for future molecular genetics studies and serological studies
Blood sample
Sponsors
NYU Langone Health
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
21 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* TB suspect with positive sputum smear
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Develop TB Blood Bank | Long-Term | To develop a bank of blood samples (serum, plasma, buffy coat DNA) and urine from patients infected with TB. This blood and urine will be used for future molecular genetics studies. Demographic data will be collected and samples will be stored by number. The banked specimens will be evaluated in an attempt to identify susceptibility genes in TB disease. Specifically, expression of the human Bcg gene that codes for resistance to M. tuberculosis will be evaluated and its expression correlated expression with gender, race, clinical TB characteristics. Each patient will have a unique identifier and therefore data generated from this analysis will not be linkable to the patient. |
Countries
United States
Outcome results
None listed