Iodixanol in Multidetector-Row Computed Tomography-Coronary Angiography (MDCT-CA)

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00209404

Enrollment

Registered

2005-09-21

Start date

2005-07-31

Completion date

Unknown

Last updated

2007-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

MDCT, Coronary Artery, Heart Rate, Image Quality, Diagnostic Quality

Brief summary

Image quality in coronary artery computed tomography is influenced by the heart rate variation during the examination. The purpose of this clinical trial is to investigate the change in heart rate following injection of a contrast medium called Visipaque™ (iodixanol). Image quality and diagnostic quality of the examination will be evaluated.

Interventions

DRUGIodixanol 320 mg I/Ml

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Subjects with low to moderate suspicion of coronary artery disease referred for retrospective electrocardiogram (ECG)-gated multidetector row computed tomography coronary angiography and with a heart rate \>75 beats per minute (bpm) will be included.

Exclusion criteria

* Subjects who take medications that slow down the heart rate or present cardiac arrhythmia at rest will not be included.

Design outcomes

Primary

Measure	Time frame
Change in mean heart rate	—

Secondary

Measure	Time frame
Image quality	—
Diagnostic quality	—
Overall diagnostic information	—
Frequency and intensity of adverse events	—

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026