Joint Outcome Study

Conditions

Hemophilia A

Brief summary

This study examines the progression of joint disease in children with hemophilia assigned to either standard treatment or enhanced therapy.

Beth Boulden Warren, Linda Jacobson, Christine L. Kempton, George R. Buchanan, Michael Recht et al. (11 authors)

Haemophilia2019-05-218 citations

10.1111/hae.13778

Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia.

Manco-Johnson MJ, Abshire TC, Shapiro AD, Riske B, Hacker MR, Kilcoyne R, Ingram JD, Manco-Johnson ML, Funk S, Jacobson L, Valentino LA, Hoots WK, Buchanan GR, DiMichele D, Recht M, Brown D, Leissinger C, Bleak S, Cohen A, Mathew P, Matsunaga A, Medeiros D, Nugent D, Thomas GA, Thompson AA, McRedmond K, Soucie JM, Austin H, Evatt BL.

2007-08-011,420 citations

10.1056/nejmoa067659

Interventions

None listed

Study design

Observational model

NATURAL_HISTORY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

1 Years to 30 Months

Healthy volunteers

No

Inclusion criteria

* Diagnosed with hemophilia A * factor level less than 2%

Exclusion criteria

* More than 2 bleeds into the same joint

Outcome results