Pre Operative Autologous Donation
Conditions
Keywords
Dubble eerythrocytapheresis
Brief summary
The project will determine the advantages of double erythrocytapheresis in the collection of preoperative autologous erythrocytes as compared to the standard collections of whole blood. The study will assess the total reduction in the number of procedures required to obtain the preoperative units ordered by the surgeon. Also, successfulness of erythrocytaphereses versus classical whole blood collection for these patients will be compared.
Detailed description
The project will determine the advantages of double erythrocytapheresis in the collection of preoperative autologous erythrocytes as compared to the standard collections of whole blood. The study will assess the total reduction in the number of procedures required to obtain the preoperative units ordered by the surgeon. Also, successfulness of erythrocytaphereses versus classical whole blood collection for these patients will be compared.
Interventions
PROCEDUREeythrocytapheresis
machinal collection of erythrocytes
PROCEDUREwhole blood collection
collection of whole blood
Sponsors
Atrium Medical Center
Maasland Hospital
Sanquin Research & Blood Bank Divisions
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Elective surgery
Exclusion criteria
* Malignancies * Severe arrhythmias * Congestive heart failure * Recent angina * Epileptic seizures in the last 3 months before collection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| decline in Hemoglobine levels | surgery |
Secondary
| Measure | Time frame |
|---|---|
| Storage parameters- ATP | 35 days |
Countries
Netherlands
Outcome results
None listed