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Training at Different Intensities in Coronary Artery Disease -Effects on Myocardial Function

Which Training Intensity is Most Effective in Improving Myocardial Function in Patients With Coronary Artery Disease?

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00201591
Enrollment
17
Registered
2005-09-20
Start date
2002-08-31
Completion date
2004-01-31
Last updated
2011-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Coronary artery disease, Exercise training, Intensity, Randomized, echocardiography, Aerobic Exercise

Brief summary

The study investigated if aerobic endurance exercise of different intensity has different impact on the physical capacity and myocardial function in patients with coronary artery disease. Patients with stable CAD trained for 10 weeks, and oxygen consumption and myocardial function were measured before and after this period. Patients were randomly assigned to each exercise group.

Detailed description

Peak oxygen consumption was measured by gas-analysis. Myocardial function was measured by echocardiography. Exercise was performed on treadmills under close supervision of an exercise physiologist. Patients had to complete over 70% of sessions to be included in analysis. Three sessions were scheduled every week. Heart rate (HR) was about 85 % of max HR in the high intensity group, and about 65 % in the moderate intensity group.

Interventions

BEHAVIORALExercise training for 10 weeks

Sponsors

St. Olavs Hospital
CollaboratorOTHER
Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* stable coronary artery disease * over 4 months since cardiovascular event

Exclusion criteria

* heart failure * inability to exercise

Design outcomes

Primary

MeasureTime frame
Peak oxygen consumption

Secondary

MeasureTime frame
Quality of life
Myocardial function measured by echocardiography

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026