Hemodynamic Measurements During Cesarean Section With Spinal Anesthesia

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00199784

Enrollment

Registered

2005-09-20

Start date

2005-06-30

Completion date

2007-04-30

Last updated

2011-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Hemodynamic, Hypotension, Spinal, Anesthesia, Healthy pregnant women for elective cesarean section

Brief summary

The purpose of this study is to determine the effect of low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion on blood pressure, cardiac output and systemic vascular resistance.

Detailed description

Hypotension during cesarean section with spinal anesthesia is common. We compare low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion.

Interventions

DRUGPhenylephrine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy pregnant women for elective cesarean section

Exclusion criteria

* Shorter than 160 or taller than 180 cm * Pre-pregnant body mass index (BMI) over 32

Design outcomes

Primary

Measure	Time frame
Differences in cardiac output	—
Blood pressure	—
Systemic vascular resistance	—

Secondary

Measure	Time frame
Nausea	—
Fatigue	—
Cardiovascular instability due to overdosing spinal anesthesia for cesarean section (CS)	—

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026