Evaluation of Two Enteral Nutrition Strategies in Mechanically Ventilated Patients

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00199641

Enrollment

100

Registered

2005-09-20

Start date

2002-07-12

Completion date

2008-01-12

Last updated

2026-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically Ventilated Patients

Brief summary

The aim of this study is to compare two strategies of early enteral nutrition in terms of efficacy and complications in mechanically ventilated patients.

Interventions

DEVICEenteral nutrition

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult (\> 18 ans) * Mechanical ventilation for \> 72 hours * Planned enteral nutrition * Informed consent

Exclusion criteria

* Body Mass Index \< 20 kg/m2 * Enteral nutrition non indicated (ileus, splanchnic ischemia..) * Shock (use of catecholamines, arterial blood pressure \< 90 mmHg, peripheral hypoperfusion, elevation of lactates \> x 1,5 normal value) * Contraindications for gastric tube * Pregnancy * Previous enrollment in the present study

Design outcomes

Primary

Measure	Time frame
Incidence of nutrition failure (diarrhea, ileus, vomiting, aspiration pneumonia, elevated residual gastric volume)	—

Secondary

Measure	Time frame
-Measured nutrition amount when compared to theorical nutrition during ICU stay	—
-Measured nutrition amount when compared to theorical nutrition during the first three days	—
-Influence of prokinetic drugs on nutrition quality	—

Countries

France

Contacts

PRINCIPAL_INVESTIGATORBruno François, MD

University Hospital, Limoges

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 10, 2026