Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00199628

Enrollment

100

Registered

2005-09-20

Start date

2005-09-30

Completion date

2014-08-31

Last updated

2019-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glomerulonephritis, Membranous, Hemochromatosis, Neonatal Diseases and Abnormalities

Keywords

fetomaternal tissular alloimmunization, Mothers having a child suffering from:, neonatal membranous glomerulonephritis, unexplained neonatal tubular defect, unexplained thrombotic microangiopathy, neonatal hemochromatosis

Brief summary

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus. The investigators recently proved that incompatibility between mother and child can concern an organ leading to a tissular alloimmunization. For example, neonatal membranous glomerulonephritis (a kidney disease) can result from this mechanism. The purpose of this network is to detect and study neonatal diseases induced by tissular fetomaternal alloimmunization. The detection of these diseases will be performed by the mother's serum analysis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

Mothers having a child suffering from: * Neonatal membranous glomerulonephritis * Unexplained neonatal tubular defect * Unexplained thrombotic microangiopathy * Neonatal hemochromatosis

Exclusion criteria

* Any cause explaining the child's disease

Countries

France

Outcome results