Skin Diseases, Infectious
Conditions
Keywords
skin cleansing, Bangladesh, Skin Flora, Newborn, infectious disease, chlorhexidine
Brief summary
Given the potential of skin cleansing with chlorhexidine as a safe, feasible, and cost-effective intervention for reducing neonatal death in developing country settings, this study follows a trial already underway in Nepal to test the impact of a single cleansing of the skin with baby wipes cotaining chlorahexidine.
Detailed description
This study is designed to test the impact of a single cleansing of the skin with 0.25% or 4.0% Chlorhexidine wipes on qualitative and quantitative skin flora and skin condition in newborn infants. The study takes place in the Special Care Nursery at Dhaka Shishu Hospital in Dhaka, Bangladesh.
Interventions
DRUGChlorhexidine
Sponsors
Johns Hopkins Bloomberg School of Public Health
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 48 Hours
Healthy volunteers
Yes
Inclusion criteria
* Infant admitted to Special Care Nursery at Dhaka Shishu Hospital less than 48 hours chronological age * parental consent must be obtained
Exclusion criteria
* infants being admitted for major surgical procedure which is attended by high rate of infectious complications * sepsis * clinically-evident skin infection * generalized skin disease * structural defect of the skin involving greater than 5% of the body surface * with a major congenital anomaly * with a known immunodeficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wiping of newborn skin will be done immediatly upon enrollment in study, with follow up during hosptial stay and up to two weeks to determine skin condition and presence of any kind of skin infection. | — |
Countries
Bangladesh
Outcome results
None listed