Lactic Acid in the Rectum and Life-Threatening Infection

Does the Concentration of L-Lactate in the Rectum Correlate With Mortality and Morbidity in Patients With Septic Shock?

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00197938

Enrollment

130

Registered

2005-09-20

Start date

2005-11-30

Completion date

2009-04-30

Last updated

2009-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic Shock

Brief summary

Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of lactic acid. The investigators hypothesize, that the more serious the condition, the higher the concentration of lactic acid will be, thus relating to the risk of multiple organ failure or death.

Interventions

PROCEDUREMeasurement of rectal lactic acid.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Fluid resuscitated septic shock \< 24 h.

Exclusion criteria

* Septic shock \> 24 h. * Pathology in the rectum. * Bleeding per rectum. * Limitation of therapy. * Where informed consent from relatives cannot be obtained.

Countries

Denmark, Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 31, 2026