Pneumococcal Infections, Meningococcal Infections
Conditions
Keywords
Streptococcus pneumoniae, Neisseria meningitidis
Brief summary
The purpose of the study is to evaluate the immune responses of UK infants after one or two doses of pneumococcal conjugate vaccine or one or two doses of three different types of meningococcal conjugate vaccine given at either two and three or two and four months of age.
Interventions
BIOLOGICALmenjugate
men C conjugate vaccine
BIOLOGICALMen C conjugate vaccine
men C conjugate vaccine
BIOLOGICALMen C conjugate
men C conjugate vaccine
BIOLOGICALMen C Conjugate
men C conjugate vaccine
Sponsors
Public Health England
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
7 Weeks to 11 Weeks
Healthy volunteers
Yes
Inclusion criteria
* Written informed consent obtained from parent or legal guardian of infant * Age 7-11 weeks at first dose
Exclusion criteria
* Any contraindications to vaccination as specified in the UK Handbook Immunisation Against Infectious Disease (Ed 1996) * \< 7 weeks or \> 11 weeks at first dose
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Immunogenicity | 3 months after last sample | SBA men C responses |
Countries
United Kingdom
Outcome results
None listed