HIV Infections, Respiratory Tract Diseases, Sepsis
Conditions
Keywords
HIV infected mothers, Infants at risk of HIV-infection, Infant lower respiratory tract disease, Infant bloodstream infection
Brief summary
The purpose of this study is to learn about lower respiratory tract and bloodstream diseases among infants born to HIV positive mothers in Botswana. Study factors include how commonly infants get these diseases, the causes, and outcomes. The study will also try to measure the protective effect, if any, of breast feeding on respiratory disease illness and deaths.
Interventions
PROCEDUREblood draws, etc.
Sponsors
Harvard School of Public Health (HSPH)
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Participation in parent study, Mashi HIV vertical transmission prevention study for pregnant Botswana women and their infants
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| OCCURRENCE OF SUSPECTED PNEUMONIA OR BLOODSTREAM INFECTION OVER FIRST TWO YEARS OF LIFE | Between birth and 2 years of life | MORTALITY; EPISODES OF SUSPECTED PNEUMONIA; BACTEREMIA; PRESENCE OF NASOPHARYNGEAL VIRAL PATHOGENS; OROPHARYNGEAL COLONIZATION WITH BACTERIAL PATHOGENS |
Countries
Botswana
Outcome results
None listed