Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00196456

Enrollment

Registered

2005-09-20

Start date

2004-04-30

Completion date

2005-01-31

Last updated

2005-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Disease

Keywords

Photodynamic lasertherapy, Periodontol disease

Brief summary

The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal patients

Detailed description

The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal pockets and to assess the reduction of subgingival bacteria. The first step will include the evaluation of the quantity of the light which will activate the photosensitizer in the various niches in the periodontal pocket. The second step will evaluate the distribution of the photosensitizer in the periodontal pocket. The third step will assess the woundhealing of the the photodynamic therapy compared to conventional periodontal therapy with an ultrasonic device.

Interventions

PROCEDUREphotosensitisation

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

35 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* systemic healthy * \>15 teeth * ≤ 6 mm \>2 teeth * age \> 35 years

Exclusion criteria

* \- systemic ill * cardiac pacemaker * \< 15 teeth

Design outcomes

Primary

Measure	Time frame
pocket depth reduction	—

Secondary

Measure	Time frame
attachmentlevel loss	—

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026