Neurodermatitis
Conditions
Brief summary
The purpose of this study is to investigate whether the treatment of acute neurodermitis with silver-contained textiles is equivalent or more effective to the conservative exogenous treatment with a corticosteroid. Secondary aim is to define skin comfortability of the textiles.
Interventions
DEVICEsilver-contained textiles
DRUGcorticosteroid
Sponsors
Julius Zorn GmbH, Aichach, Germany
University Medicine Greifswald
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Age
2 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of acute Neurodermitis * Age: 2-70 years * Patients are mobile * Patient's information and willingness to participate
Exclusion criteria
* Acute viral infection (herpes zoster, eczema herpeticum) * Acute staphylodermas * Other skin-diseases affecting outcomes of intervention (e.g. psoriasis) * Current UV-Treatment * Current other immunosuppressive or immunomodulated Therapy * Current antimicrobial Therapy (e.g. antibiotics) * Severe general diseases (e.g. melanoma, renal insufficiency, autoimmune diseases) * Pregnancy * Fertile females without effective contraception
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SCORAD at days -3,0,7,14,28,56 for every group | — |
Secondary
| Measure | Time frame |
|---|---|
| Influence of silver containing textiles in reducing bacterial skin colonization (especially Staph. aureus) | — |
| Consumption of corticosteroids at days 0-28 | — |
| Consumption of corticosteroids at days 28-56 | — |
| Pruritus under textiles | — |
| Evaluation of quality of life | — |
Countries
Germany
Outcome results
None listed