Gastroesophageal Reflux, Sleep Apnea
Conditions
Brief summary
Patients with a clinically indicated sleep study will be enrolled in this study. They will have a diagnostic and a therapeutic sleep study with continuous positive airway pressure ventilation. For both studies a pH probe will be placed nasal to measure the amount of acidic reflux during each study. Baseline levels of reflux from the diagnostic sleep study will be compared to reflux episodes while on continuous positive airway pressure ventilation.
Interventions
CPAP ventilation is a therapeutic modality which uses positive pressure of air through a sealed nasal mask to treat a condition known as sleep apnea
Sponsors
University of Pennsylvania
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* 18-75 years of age, symptoms consistent with sleep apnea, agree to consent form and placement of pH probes
Exclusion criteria
* any unstable medical condition, previous upper gi surgery or anatomic abnormality of upper gi tract, acid suppressing medication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Decrease in GERD symptoms | 24 hours | Patients suffering from Obstructive Sleep Apnea have been shown to suffer from GERD events more frequesntly and with prolonged episodes compared to controls. |
Countries
United States
Outcome results
None listed