The Serotonergic Transmitter System in Dementia and Affective Disorders

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00192998

Enrollment

100

Registered

2005-09-19

Start date

2003-10-31

Completion date

Unknown

Last updated

2007-09-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer Disease, Mood Disorders

Keywords

Affective disorder, Alzheimer dementia, healthy controls

Brief summary

The aim of this project is to examine the serotonergic transmitter system using functional imaging of the brain (positron emission tomography \[PET\]) to gain knowledge about early pathophysiological changes in Alzheimer's dementia and mood disorders.

Interventions

None listed

Study design

Observational model

DEFINED_POPULATION

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Moderate to severe Alzheimer's disease * Individuals genetically predisposed to affective disorder * Healthy gender and age matched controls

Exclusion criteria

* Contraindications to magnetic resonance imaging (MRI) * Use of psychoactive drugs * Past or present affective disorder * Other systemic diseases that may affect brain function

Countries

Denmark

Contacts

Primary ContactVibe G. Frokjaer, MD

vibe@nru.dk+45 3545 6714

Backup ContactSteen G. Hasselbalch, MD

sgh@nru.dk

Outcome results