Gemcitabine/Platinum Containing Regimens as Preoperative Chemotherapy for Patients With Non Small Cell Lung Cancer

A Randomized Phase II Trial of Gemcitabine Containing Regimens (Gemcitabine/Carboplatin and Gemcitabine/ Cisplatin)When Used as Preoperative Chemotherapy for Patients With Stage I and II NSCLC

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00191230

Enrollment

Registered

2005-09-19

Start date

2001-09-30

Completion date

2006-07-31

Last updated

2007-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carcinoma, Non Small Cell Lung

Brief summary

To study the efficacy and tolerability of gemcitabine/platinum chemotherapy in non small cell lung cancer

Interventions

DRUGgemcitabine

DRUGcarboplatin

DRUGcisplatin

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Histologically of cytologically confirmed non small cell lung cancer * No prior chemotherapy or radiation * No prior malignancy

Exclusion criteria

* Pregnant or breastfeeding * Serious concomitant systemic disorder

Design outcomes

Primary

Measure	Time frame
Complete pathological response	—

Secondary

Measure	Time frame
Response rate, disease free survival, toxicity including pulmonary toxicity,operative mortality and quality of life.	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026