Light Based Analysis of Developing Breast Tissue in Adolescent Girls: a Feasibility Study

Pilot Study to Investigate the Feasibility of Optical Spectroscopy to Quantify Bulk Breast Tissue Properties in Girls Age 10 - 14 Years

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00188591

Enrollment

Registered

2005-09-16

Start date

2005-04-30

Completion date

2008-11-30

Last updated

2008-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Keywords

Optical Transillumination Spectroscopy, Breast Cancer Risk

Brief summary

The proposed pilot study attempts to investigate the feasibility of Optical Spectroscopy (OS) as a method to quantify breast tissue composition and density in adolescent females. Our goals include: to assess whether adolescent girls can be instructed to assist with the OS measurement procedure and to determine the OS technique's ability to show breast tissue composition and density in adolescent breast tissue.

Detailed description

The period between menarche and the age of first full-term pregnancy has been identified as being most crucial for establishing an individual's future breast cancer risk. Epidemiological studies further suggest exposures, such as foods and toxins, during adolescence to have a significant impact on the likelihood of transformation in the developing breast resulting in cancer later in life. Adolescent diet affects mammary development directly and indirectly by influencing the micronutrients and the hormonal status of the adolescent. The goal of this study is to investigate the feasibility of Optical Spectroscopy (OS), a method based on differential light scattering and absorption in tissue, to quantify bulk breast tissue properties in adolescent females.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

10 Years to 14 Years

Healthy volunteers

Yes

Inclusion criteria

(Girls): * Are in good health and are able to provide assent * Are between the ages of 10 and 14 * Are interested in participating in this study * Are willing to come, accompanied by a parent, to the Princess Margaret Hospital Inclusion Criteria (Parents): * Are able to provide consent * Are willing to accompany your daughter to the Princess Margaret Hospital for one visit of about 45 minutes

Exclusion criteria

(Girls): * Have had previous surgeries to the chest area

Countries

Canada

Outcome results