Asthma
Conditions
Brief summary
Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.
Detailed description
A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.
Interventions
DEVICEmagnetic resonance imaging (MRI) of the thorax
Sponsors
University Health Network, Toronto
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* All asthmatic patients are eligible.
Exclusion criteria
* Patients in whom MRI is contraindicated
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests | — |
Countries
Canada
Outcome results
None listed