Abortion, Induced
Conditions
Keywords
medical abortion, analgesia
Brief summary
* To compare postoperative analgesia by paracetamol 1gr or ketoprofen 100 mg or the combination of these two analgesics * each treatment beeing allocated by randomization
Detailed description
* 240 pregnant women who undewent a medical abortion by aspiration, under local anesthesia, (day case surgery) were enrolled after informed consent and signed approval * according to randomization, they received one hour before medical abortion procedure performed under local anesthesia of the cervix, one of these three diffrente analgesics : * paracetamol 1 gr * ketoprofen 100 mg * the association of both Postprocedure pain was recorded, by nurse, using a visual analog scale (VAS), 7 times before and after the procedure, until the discharge of the patient. * if VAS was above 40 on two consecutive measurements a morphine injection was given. * the number and total amount of morphine was recorded. * satisfaction was recorded within the 3 postoperative day by a telephone inquiry.
Interventions
DRUGparacetamol
DRUGketoprofen
DRUGketoprofen + paracetamol
Sponsors
University Hospital, Angers
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* pregnant women * medical abortion performed in day case surgery under local anesthesia * informed written consent
Exclusion criteria
* under 18 year old
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain rating | — |
Secondary
| Measure | Time frame |
|---|---|
| morphine consumption | — |
| patient satisfaction | — |
Countries
France
Outcome results
None listed