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Continued Early Intervention for Recent-onset Schizophrenia

Continued Early Intervention for Recent-onset Schizophrenia. A Randomized Controlled Study.

Status
Terminated
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00184509
Enrollment
50
Registered
2005-09-16
Start date
1993-02-28
Completion date
1998-05-31
Last updated
2017-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Keywords

schizophrenia, psychosocial treatment, outcome

Brief summary

The purpose of this study was to determine whether outreach integrated treatment of first episode schizophrenia was more effecive than standard outpatient treatment.

Detailed description

Early intervention for schizophrenia has spawned considerable enthusiasm among clinicians without solid research evidence to suport its benefits and costs. The present study is a random-controlled study of integrated biomedical and psychosocial treatment on a population of recent-onset cases. Comparison(s): 50 consecutive referrals with schizophrenic disorders of less than two years duration were allocated randomly to a comprehensive model of integrated treatment or standard care for two years. Main outcome measures was psychopathology, psychosocial functioning and hospital admissions.

Interventions

BEHAVIORALintegrated psychosocial treatment (behavior)

Sponsors

The Research Council of Norway
CollaboratorOTHER
Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
No

Inclusion criteria

* first-episode schizophrenia

Exclusion criteria

* acute psychosis

Design outcomes

Primary

MeasureTime frame
Rehospitalizations and psychotic relapse at two years

Secondary

MeasureTime frame
Psychopathology, psychosocial changes, functioning, antipsychotic medication

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 7, 2026