Depression Prevention Program for American Indian Adolescents During and After Pregnancy

Depression Prevention in Pregnant American Indian Teens Using CBT

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00183547

Enrollment

Registered

2005-09-16

Start date

2005-01-31

Completion date

2007-09-30

Last updated

2013-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Pregnancy

Keywords

Postpartum Depression, Postpartum Period, Indians, North American, Adolescent, Female, CBT

Brief summary

This study will determine the effectiveness of the Living in Harmony depression prevention program in preventing depressive symptoms among pregnant American Indian adolescents during pregnancy and after giving birth.

Detailed description

Pregnancy among reservation-based American Indian adolescents has become increasingly common. Numerous psychosocial and environmental factors have put this population at high risk for pregnancy-related depression. Depression during pregnancy and after giving birth is associated with reduced quality of life for both young mothers and their children. Many reservations lack mental health services; therefore, an inexpensive intervention is needed to prevent depressive symptoms among pregnant adolescents who live on reservations. The duration of this study will vary for each participant, depending on the time of study entry. Participants will be randomly assigned to receive weekly sessions of either the Living in Harmony program, consisting of cognitive behavioral therapy (CBT), culturally-relevant education, and support; or general depression-prevention education and support. Participants' depressive symptoms will be assessed at study entry, at 4, 12, and 24 weeks after giving birth, and study completion. Interviews and self-report scales will be used to assess participants.

Interventions

BEHAVIORALLiving in Harmony depression prevention program

Weekly therapy sessions consisting of cognitive behavioral therapy (CBT), culturally-relevant education, and support

BEHAVIORALDepression-prevention education and support

Weekly therapy sessions offering general depression-prevention education and support

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

15 Years to 19 Years

Healthy volunteers

Yes

Inclusion criteria

* At 28th week or earlier of pregnancy * Center for Epidemiologic Studies-Depression Scale (CES-D) score of 16 or higher * Identified (by others and by self) as an American Indian * Currently live on an American Indian reservation * Parent or guardian willing to give consent, if applicable * Willing and able to comply with all study requirements

Exclusion criteria

* Diagnosis of major depressive disorder * Current psychiatric disorder or condition requiring intervention or treatment * Current participation in another mental or behavioral health study

Design outcomes

Primary

Measure	Time frame
Postpartum depression	up to 24 weeks postpartum

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026