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Depression Prevention Program for Adolescents

Depression Prevention Program for High-Risk Adolescents

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00183417
Enrollment
350
Registered
2005-09-16
Start date
2004-09-30
Completion date
2009-05-31
Last updated
2012-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Keywords

Adolescent, CBT

Brief summary

This study will compare the effectiveness of two programs designed to prevent depression in adolescents.

Detailed description

Major depression is one of the most common psychiatric disorders in adolescents. In many cases, the condition is recurrent and can result in serious psychological impairment. A high number of depressed adolescents never receive treatment; therefore, it is crucial to develop prevention programs for this disorder that are effective and can be easily disseminated. This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT) and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents. This study will last 2 years. Participants will be randomly assigned to receive six sessions of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention will focus on reducing negative thoughts and increasing engagement in pleasant activities. S/E therapy is designed to allow adolescents to express their negative emotions and talk about recent stressful events in a supportive environment of their peers. Surveys and psychiatric interviews will be completed by all participants and their parents at the beginning and the end of the study. The surveys and interviews will assess depressive symptoms.

Interventions

Participants will complete worksheets and group discussion on how to increase positive mood and activity.

BEHAVIORALSupportive/expressive (S/E) therapy

Participants will be encouraged to express feelings and emotions without advice giving.

BEHAVIORALBibliotherapy

Participants will be given a book on how to increase their mood.

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
University of Texas at Austin
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
14 Years to 18 Years
Healthy volunteers
Yes

Inclusion criteria

* Beck Depression Inventory score higher than 10 * Parent or guardian willing to provide informed consent

Exclusion criteria

* Diagnosis of depression

Design outcomes

Primary

MeasureTime frame
Depressive symptomsMeasured at Year 1

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026