Healthy
Conditions
Keywords
nitric oxide, volumetric oxygen consumption
Brief summary
The purposes of this study are: 1. To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults. 2. To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation. Since stress is a factor in the development of many health conditions, a further understanding of the mechanisms of the RR should be developed. The project is designed to determine how the RR can improve the quality of life that has been adversely affected by stress.
Detailed description
The purposes of this study are: 1. To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults. 2. To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation. Since stress is a factor in the development of many health conditions, a further understanding of the mechanisms of the RR should be developed. The project is designed to determine how the RR can improve the quality of life that has been adversely affected by stress.
Interventions
BEHAVIORALrelaxation response- meditation
Sponsors
Centers for Disease Control and Prevention
Beth Israel Deaconess Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE
Eligibility
Sex/Gender
ALL
Age
18 Years to 49 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy individual * age:18-49 years * able to read and understand English * able to attend al study visits * access to a telephone (to schedule visits)
Exclusion criteria
* current smoking * asthma * current use of any prescription or psychoactive medications or supplements * either: 1. no prior experience with RR eliciting techniques 2. at least 3 years of regular RR elicitation (at least 20 min/day) * BMI \>30 * exhaled nitric oxide levels \>60 ppb * abnormal lab values (Hct \<32,creatinine \>1.3, glucose \>200 * pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation. | — |
Countries
United States
Outcome results
None listed