Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant

Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant (HSCT)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00179049

Enrollment

100

Registered

2005-09-15

Start date

2003-04-30

Completion date

2008-04-30

Last updated

2008-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Graft vs Host Disease, Hematopoietic Stem Cell Transplantation

Keywords

T-Lymphocyte Subsets

Brief summary

The investigators' hypothesis is that the graft-versus-tumor effect can be enhanced while minimizing the complications of graft-versus-host disease.

Detailed description

The investigators' hypothesis is that the graft-versus-tumor effect can be enhanced while minimizing the complications of graft-versus-host disease (GVHD) by determining the qualitative and quantitative changes in T regulatory cells throughout the transplant process. Their understanding of this can lead to new treatment strategies and improved clinical therapeutic implications.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients 18-70 years old undergoing either autologous transplant or allogeneic transplant for various hematologic conditions

Exclusion criteria

* Patients \< 18 or \> 70 years old undergoing either autologous transplant or allogeneic transplant

Countries

United States

Outcome results