Bipolar Disorder, Major Depression, Schizoaffective Disorder, Schizophrenia
Conditions
Brief summary
The goals of this study are to replicate previous findings of genetic predictors of response to clozapine and other antipsychotic drugs.
Interventions
PROCEDUREgenetic analysis
genetic assay of blood sample drawn with patient's consent
PROCEDUREgenetic assay
genetic assay of blood sample drawn with patient's consent
Sponsors
Northwestern University
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Patients with the diagnoses of schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features, or volunteers with no history of a psychotic disorder.
Exclusion criteria
Patients with DSM-IV diagnoses other than schizophrenia or schizoaffective disorder, and bipolar disorder or major depression with psychotic features.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We plan to compare the polymorphisms across schizophrenic patients and adults who do not have a diagnosed major mental illness. . | single visit |
Secondary
| Measure | Time frame |
|---|---|
| We will also evaluate relationships between the polymorphism and past and current mental health among the non-diagnosed sample | single visit |
Countries
United States
Outcome results
None listed