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Effects of Comorbid Personality Disorder on the Treatment of Bipolar I Disorder

Treatment of Primary Mood Disorders in the Comorbidly Ill

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00178061
Enrollment
13
Registered
2005-09-15
Start date
1997-08-31
Completion date
2002-08-31
Last updated
2013-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar I Disorder, Borderline Personality Disorder

Brief summary

This study will examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.

Detailed description

The major aim of this proposal is to examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder. The specific aims are to create a research and supervisory team and to identify potential moderators of treatment response and mediators of outcome over the course of treatment. Members of the team will meet weekly to begin a treatment development process for enhancing Interpersonal Social Rhythm Therapy (IPSRT) for these patients. Additional assessment measures will be utilized to examine the proposed mediators and moderators of treatment.

Interventions

Sponsors

University of Pittsburgh
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Bipolar I Disorder with Comorbid Borderline Personality Disorder, currently manic or depressed

Exclusion criteria

* Unstable Medical illness

Design outcomes

Primary

MeasureTime frame
Hamilton Rating Scale for Depression (HRSD-25)

Secondary

MeasureTime frame
Raskin Severity of Depression and Mania Scales

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026