Obesity, Weight Loss
Conditions
Brief summary
The purpose is to examine varying durations and intensities of exercise on long-term weight loss.
Interventions
BEHAVIORALbehavior weight loss
Sponsors
National Institutes of Health (NIH)
University of Pittsburgh
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
21 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
1. Female 2. 21-45 years of age 3. BMI = 27-40 kg/m2 4. Ability to provide informed consent. 5. Ability to provide consent from their personal physician to participate in this study.
Exclusion criteria
1. Reporting regular exercise participation of at least 20 minutes per day on at least 3 days per week during the previous six months. (This study is designed to recruit relatively sedentary adults.) 2. Diabetes, hypothyroidism, or other medical conditions which would affect energy metabolism. 3. Currently pregnant, pregnant within the previous six months, or planning on becoming pregnant within the next 24 months. (Pregnancy will be based on self-report and will be included on the detailed medical history that is completed by subjects.) 4. Non-medicated resting systolic blood pressure \>160 mmHg or non-medicated resting diastolic blood pressure \>100 mmHg, or taking medication that would affect blood pressure. 5. Taking medication that would affect resting heart rate or the heart rate response during exercise (e.g., beta blockade). 6. Arrhythmia on resting or exercise electrocardiogram that would indicate that vigorous exercise was contraindicated. 7. History of myocardial infarction or valvular disease. 8. History of orthopedic complications that would prevent optimal participation in the exercise component (e.g., heel spurs, severe arthritis).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weight loss | — |
Secondary
| Measure | Time frame |
|---|---|
| fitness | — |
| dietary intake | — |
| physical activity | — |
| mediators | — |
| body composition | — |
Countries
United States
Outcome results
None listed